Stability of the Human Immunodeficiency Virus-1 Reverse Transcriptase Heterodimer
The characterization of a heteroassociating system is described in this article:
• The thermodissociation is studied using band sedimentation analysis;
• The electrostatic dissociation is studied using boundary sedimentation analysis.
The heterodimer stability of human immunodeficiency virus-1 (HIV-1) reverse transcriptase (RT) was examined recently(1) by sedimentation equilibrium and velocity methods as a function of temperature and ionic strength.