Automated Online-Solution for Vi CELL XR Cell Viability Analyzers
In order for automated online cell analysis to be an effective process PAT tool, certain criteria need to be met. First, the technology should provide rapid and accurate cell analysis that performs as good as, or better than, the manual off-line analytical method. Second, it should reduce analytical variability and sample contamination due to manual sampling and operator-to-operator error.6 Third, it should facilitate a scale-independent strategy that allows the same analytical instrumentation to be used from the laboratory through production. Fourth, the technology should allow the integration of other third-party analyzers, i.e., HPLC, biochemistry analyzers, to facilitate a comprehensive PAT platform. Lastly, the real-time data generated by the cell analyzer should be seamlessly integrated into the process supervisory control and data acquisition (SCADA) or bioprocess management system.